BiomarkersFree T3

Thyroid

Free T3

The most active thyroid hormone

On your report it may say: FT3, Free triiodothyronine

T3 is the most active thyroid hormone, mostly made by converting T4 in body tissues. It's useful when an overactive thyroid is suspected.

Updated 2026-10-26

Typical ranges · pg/mL

Low below 2.3
In range 2.3–4.2
High 4.2+

pmol/L = pg/mL × 1.536

T3 falls during illness, fasting or heavy calorie restriction.

Ranges vary by lab, age and sex. The range printed on your report applies.

If it's low

Can reflect an underactive thyroid or recent illness or dieting.

Common causes

  • Underactive thyroid
  • Illness or crash dieting

What you might notice

  • Tiredness
  • Feeling cold

If it's high

Often seen with an overactive thyroid.

Common causes

  • Overactive thyroid
  • Excess thyroid medicine

What you might notice

  • Fast heartbeat
  • Anxiety
  • Weight loss

Testing

Who should test
When an overactive thyroid is suspected or results are unclear.
How to prepare
Stop biotin 2–3 days before.
When to retest
As your doctor advises.

What can help

SYNC doesn't recommend supplements from thyroid results. Thyroid problems need a doctor's diagnosis and treatment.

See a doctor about abnormal results.

Common questions

Does selenium raise T3?

Selenium helps conversion, but supplements aren't a thyroid treatment.

Why is T3 low when I'm unwell?

The body lowers T3 temporarily to save energy.

Explore further

Sources

  1. MedlinePlus (US National Library of Medicine): Triiodothyronine (T3) tests

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For general education only, not medical advice. Ranges shown are typical for adults; the range printed on your lab report applies. Talk to a qualified doctor about your results.