BiomarkersRBC folate

Vitamins

RBC folate

Longer-term folate status, held in red blood cells

On your report it may say: Red blood cell folate

RBC folate measures folate stored inside red blood cells, which reflects the last 2–3 months rather than recent meals. It's the better test for planning pregnancy.

Updated 2026-10-26

Typical ranges · ng/mL

Low below 140
In range 140–400
Pregnancy target 400+

nmol/L = ng/mL × 2.266

For women planning pregnancy, about 400 ng/mL (906 nmol/L) or more is the target linked to lower neural tube defect risk.

Ranges vary by lab, age and sex. The range printed on your report applies.

If it's low

Folate stores have been low for weeks to months.

Common causes

  • Long-term low intake
  • Alcohol
  • Malabsorption
  • Medicines that block folate

What you might notice

  • Anaemia
  • Tiredness
  • Mouth sores

If it's high

High levels reflect good intake or supplements.

Common causes

  • Supplements
  • Fortified foods

What you might notice

  • No symptoms

Testing

Who should test
Women planning pregnancy, and anyone whose serum folate result is unclear.
How to prepare
No fasting needed.
When to retest
After 3 months of a supplement.

What can help

Food sources

Leafy greensPulsesCitrus fruit

Talk to your doctor before conception if your level is below the pregnancy target.

Common questions

Why does it take months to change?

Red blood cells live about 120 days, so stores rise gradually.

Is it routinely tested?

Not often. Ask for it specifically if you're planning a pregnancy.

Explore further

When to take them

Sources

  1. NIH Office of Dietary Supplements: Folate fact sheet for health professionals

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For general education only, not medical advice. Ranges shown are typical for adults; the range printed on your lab report applies. Talk to a qualified doctor about your results.