TimingPhosphatidylserine

Take with meals

When to take Phosphatidylserine

With a meal; evening for stress

Phosphatidylserine is a fat in brain cell membranes. It's used for memory and to calm the stress-hormone response, so evening is useful for stress.

Updated 2026-10-25

Best time in your day

  1. Wake
  2. Workout
  3. Breakfast
  4. Lunch
  5. Evening
  6. Workout
  7. Dinner
  8. Walk
  9. Bed
When
With meals; evening for stress
Food
With food
Typical dose
100–300 mg per day, split

How to take it

  1. 1Choose sunflower or soy-derived products
  2. 2Take it with meals
  3. 3Use an evening dose for stress or sleep
  4. 4Use for 6–12 weeks

Watch out

Mild stomach upset or insomnia can occur at high doses.

Keep apart from

  • Blood thinners (ask first)

Common questions

Does it help with cortisol?

Some studies show it blunts cortisol spikes after stress.

Is it good for memory?

Evidence is strongest in older adults.

Soy or sunflower?

Both work; sunflower avoids soy allergy.

Explore further

SYNC check

Get your timing plan

Tell us what you take and we'll arrange it into a simple daily routine.

Build my routine

For general education only, not medical advice. Talk to a qualified doctor before starting or changing supplements, especially if you are pregnant, nursing or on medication.