TimingMagnesium L-Threonate

Best in the evening

When to take Magnesium L-Threonate

Evening

Magnesium L-threonate is designed to cross into the brain and is studied for memory and sleep. It provides less elemental magnesium, so it won't fix a deficiency alone.

Updated 2026-10-25

Best time in your day

  1. Wake
  2. Workout
  3. Breakfast
  4. Lunch
  5. Evening
  6. Workout
  7. Dinner
  8. Walk
  9. Bed
When
Evening
Food
With or without food
Typical dose
1.5–2 g compound (about 145 mg elemental) per day

How to take it

  1. 1Take it 1–2 hours before bed
  2. 2Split it morning and evening if desired
  3. 3Pair it with another form if you're deficient
  4. 4Use for 6–12 weeks

Watch out

Drowsiness or headache can occur. Check with your doctor if you have kidney disease.

Keep apart from

  • Antibiotics (2–4 hours)
  • Bisphosphonates (2 hours)

Common questions

Is it better than glycinate for sleep?

Glycinate is cheaper and well studied; threonate targets the brain.

Is the evidence strong?

Human studies are small but promising.

Why is the elemental amount low?

Threonate is a big molecule.

Explore further

Commonly used for

Sources

  1. NIH Office of Dietary Supplements: Magnesium fact sheet for health professionals

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For general education only, not medical advice. Talk to a qualified doctor before starting or changing supplements, especially if you are pregnant, nursing or on medication.