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Strong evidenceVitamins

Folate

Also called: Methylfolate (L-5-MTHF), folic acid, vitamin B9

A B vitamin vital before and during pregnancy, and for red blood cells. Always check B12 alongside it.

Typical amount
200–400 mcg a day (RDA 220–300 mcg)
Best time
Morning · Timing guide
Food
With or without food
Typical course
12 weeks, then review
Upper limit
1,000 mcg a day from supplements unless a doctor prescribes more
Is it right for me?

Where to buy

3 products
Also inside 7 other products (combinations and multivitamins)

What is folate?

Folate helps make DNA and red blood cells. Before and in early pregnancy, enough folate greatly reduces the risk of neural tube defects. Methylfolate is the active form; folic acid is the synthetic form used in most supplements and fortified foods. High folate can hide a B12 deficiency.

Forms. Folic acid tablets, methylfolate, and combinations with B12. Pregnancy doses are set by a doctor.

What it may help with

Evidence grade

Strong: several good human trials. Moderate: some trials, mixed results. Limited: small or early studies. Traditional: long use, little trial evidence.

Safety and interactions

Side effects
Safe at usual doses. More than 1,000 mcg a day from supplements can mask low B12.
Who should be careful
Check B12 too (folate can hide B12 deficiency); pregnancy dosing per doctor
Medicines
Ask your doctor first if you take steroids or immunosuppressants. Ask your doctor first if you take pregnancy or breastfeeding.
Stop and call a doctor if
Rash

Food sources

Green leafy vegetables, dals, chana, rajma, oranges, beetroot and fortified foods.

Common questions

When should women start folate?

At least 1–3 months before trying to conceive. Ask your gynaecologist for the dose.

Methylfolate or folic acid?

Both work for most people; methylfolate is the active form.

Why check B12?

Folate can hide the anaemia of B12 deficiency while nerve damage continues.

Sources

For information only, not medical advice. Prices and links are checked by hand and can change; we may earn a small commission on some links. This plan is based on your answers and is not a medical diagnosis. It does not replace advice from your doctor. If you take medicines or have a health condition, check with your doctor before starting any supplement.