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Limited evidenceSkin & hair

Glutathione

Also called: L-glutathione, GSH

The body's main antioxidant. Popular for skin, but evidence for oral supplements is modest.

Typical amount
250–500 mg a day
Best time
Morning
Food
Empty stomach
Typical course
12 weeks, then review
Upper limit
600 mg a day (FSSAI limit per Regulyze)
Is it right for me?

Where to buy

3 products
Also inside 1 other product (combinations and multivitamins)

What is glutathione?

Glutathione is made in every cell and helps neutralise oxidative stress. Oral supplements are popular in India for skin, though it's debated how much survives digestion. Glutathione injections for skin lightening are not approved and carry real risks.

Forms. Tablets, effervescents and liposomal forms, often combined with vitamin C. FSSAI permits oral doses up to about 600 mg a day.

What it may help with

Evidence grade

Strong: several good human trials. Moderate: some trials, mixed results. Limited: small or early studies. Traditional: long use, little trial evidence.

Safety and interactions

Side effects
Generally well tolerated orally. Avoid injections for skin lightening.
Who should be careful
Asthma: some people react to inhaled forms; evidence for oral use is modest. Don't use 'whitening' claims
Stop and call a doctor if
Rash, wheezing

Food sources

The body makes it from protein. Sulphur-rich foods (onion, garlic, cruciferous vegetables) and whey support production.

Common questions

Does glutathione lighten skin?

Evidence for oral use is weak; SYNC doesn't make whitening claims. Sunscreen does more for even skin tone.

When should I take it?

Morning, on an empty stomach, or as the label says.

Is it safe?

Oral doses up to about 500 mg a day are generally well tolerated.

For information only, not medical advice. Prices and links are checked by hand and can change; we may earn a small commission on some links. This plan is based on your answers and is not a medical diagnosis. It does not replace advice from your doctor. If you take medicines or have a health condition, check with your doctor before starting any supplement.