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Moderate evidenceAdaptogens

Ashwagandha

Also called: Withania somnifera, Indian ginseng; KSM-66 and Sensoril are standardised extracts

India's best-known adaptogen. Studied for stress, sleep and recovery, with effects building over 6–8 weeks.

Typical amount
300–600 mg standardised root extract a day
Best time
Evening (or morning) · Timing guide
Food
With food
Typical course
8 weeks, then review
Upper limit
600 mg extract a day; use in 8–12 week cycles
Is it right for me?

Where to buy

3 products
Also inside 6 other products (combinations and multivitamins)

What is ashwagandha?

Ashwagandha is a root used in Ayurveda for centuries as a rasayana (rejuvenating herb). Modern trials, mostly with standardised extracts like KSM-66, suggest it can lower perceived stress and cortisol and improve sleep. It isn't for everyone: it can affect thyroid hormones and interact with several medicines, and rare cases of liver injury have been reported.

Forms. Standardised root extract capsules (KSM-66, Sensoril) are best studied. Plain root powder (churna) is weaker per gram.

What it may help with

Evidence grade

Strong: several good human trials. Moderate: some trials, mixed results. Limited: small or early studies. Traditional: long use, little trial evidence.

Safety and interactions

Side effects
Drowsiness, stomach upset or loose stools. Rare liver injury: stop if you notice yellow eyes or dark urine. Avoid in pregnancy, hyperthyroidism and autoimmune disease.
Who should be careful
Pregnancy, breastfeeding, hyperthyroidism, autoimmune disease: avoid; thyroid, sedative, diabetes, BP and immunosuppressant medicines: doctor first; rare liver injury reports
Medicines
Ask your doctor first if you take thyroid medicine. Ask your doctor first if you take diabetes medicine. Ask your doctor first if you take blood pressure medicine. Ask your doctor first if you take antidepressants or sleeping pills. Avoid if you take steroids or immunosuppressants. Ask your doctor first if you take pregnancy or breastfeeding.
Stop and call a doctor if
Yellow eyes or skin, dark urine, palpitations, unusual drowsiness

Food sources

Not found in everyday foods.

Common questions

How long does ashwagandha take to work?

Most trials see effects after 6–8 weeks. Use it in cycles of 8–12 weeks, then reassess.

Can I take it with thyroid medicine?

Only with your doctor's agreement, because it can change thyroid hormone levels.

Morning or night?

Evening suits sleep and stress; morning is fine if it doesn't make you drowsy.

Sources

For information only, not medical advice. Prices and links are checked by hand and can change; we may earn a small commission on some links. This plan is based on your answers and is not a medical diagnosis. It does not replace advice from your doctor. If you take medicines or have a health condition, check with your doctor before starting any supplement.